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KKKKK___8_E*:Y#Tw,)))))))$W,/J)QKYY)KKH)!$!$!$KK)!$)!$!$&P&p}*R3"d&t)*0E*$&,W/"W0P&P&W/30$Kd&!$))!$E*W0 I : ˆ}v(Nv] z zYef['Y~ zW,gOo`Course Information  zNxCourse Code BI487*f[eCredit Hours 32*f[RCredits 2* zTyCourse Title -Ne ˆ}v(Nv] ze Functions and Applications of Proteins & Enzymes* z'`(Course Type W{QRQ zc[aTarget Audience uir] z0uirb/gNN,gyu*c(Language of Instruction)-Ne*_b|School u}Tyf[b/gf[bHQO zPrerequisite  0uirSf[ 00 0 g:gSf[ 00 0_uirf[ 00 0RP[W Of[ 0Biochemistry, Organic chemistry, Microbiology, Molecular geneticscYe^Instructor 1u_g zQ@W(Course Webpage)ftp://public.sjtu.edu.cn/* z{NDescription  ,g z\cON*N[ˆ}v(R0S%cRv:g6RNSvQ^(uv~N NN;N\Sbˆ}v(Rv~gW@x0ˆ}v(Tvv\O(u:g6R0ˆ}v(bST~ň0ˆ}v(ыT[MONOp0ˆ}v(Sf[0ˆ}v(͑~hNRy0ˆ}v(h_0ˆ}v(Rnxel0ˆ}v(vN\O(uSvQVP[0ˆ}v(NvvRP[9e N^(u0 zv;Nvv/fOcf[utv^ccˆ}v(yf[vW,gt q`ˆ}v(Tv(uNuN g(uir(@bv~T'`v f[yvel0Nˆ}v(yf[vsQeۏU\TxQW[O bU\[uiryf[vsQWv`~RT~TƉΑ0* z{NDescription Thiscoursewill provide a detailed understanding of the functional properties, functional mechanism and applications of proteins and enzymes, and will include topics such asstructural foundation of functional proteins, mechanism of protein action, protein localization and posttranslationalmodification, proteinchemistry, proteinisolation and recombination expression, characterisation techniques, protein-ligand andprotein-proteininteractions, strategyforengineeringproteins, and applications of proteins and enzymes. the purpose of the course is to give biological engineering undergraduates an understanding and an overview of the subject of protein science. The fundamentals of enzyme-catalyzed reactions will be introduced, especially as they apply to large scale production of small molecules. This course aims to familiarize participants with the integrated, interdisciplinary approach required to utilize the functional proteins and enzymes for applications. zYef['Y~course syllabus *f[`Nvh(Learning Outcomes)(1) ccˆ}v(yf[vi_0srTcb0(2) |~0W_ˆ}v(v~gTReb~TwƋ0(3) tˆ}v(xvz-N@bO(uvuirb/gvtwƋ0(4) _Nˆ}v(Tˆ}v(~f[xvzvsQvb0(5) _ċ0ONNxvzpencTQHrevRgR0(6) q`v^(uNuirPSvOpTP6RV }0(7) q~0Wcc͑~ˆ}vKQTh0(8) cc'Yĉ!j]N^(uvvPSS^0(9) Scuirf[eHh(uN㉳Qv(uNuirPSvP6RV }0 (1) Understanding purpose, status, perspective, and challenges of protein science.(2) To gain a comprehensive knowledge of the structure and function of proteins.(3) An advanced Understanding theoretical knowledge of the biotechniques used in the stu TX`d|~ƻzpkzc\Uz hgrh*& h<h:h<h<o( h<o(hgrh:RHZo(hgrh0B*o(phhgrh:RHZhERHZo( hERHZ hgrh:hgrh:o( hgrh hgrh o(h^h^CJ aJ h 5CJ aJ h h 5CJ aJ h^h 5CJ aJ hTk5CJ aJ o(h<h<5CJ aJ o( VXb~qee\eee $Ifgd) $$Ifa$gdgrykd$$Iflf;#&  t 0&644 lap ytgr $$Ifa$gdgr$a$gd^  $$Ifa$gd< $$Ifa$gdgrkd$$Ifl/ֈ; }BY#f  t0&644 lap<ytgr    `TK $Ifgd8L $$Ifa$gdgrkd$$Ifl40;#f ^ t0&644 lapytgr $Ifgd^ $$Ifa$gdgr    &       P R V Z \ d f v x 跬褝~ql h<o(hgrh0B*o(phhUh<o(h,h<o( h,h<hgrh}o( hgrhilhgrhilo(hgrh B* phP hTko(hgrh^B*o(phh8Lh8LCJQJh<h<CJaJo(hgrhCiho( hgrh hgrh o(hgrh^o(* uii] $$Ifa$gdTk $$Ifa$gdgrkd]$$Ifl40;# f ^ t0&644 lapytgr  vjj^ $$Ifa$gdTk $$Ifa$gdgrkd$$Ifl0;#f ^ t0&644 lapytgr   R X xl`T $$Ifa$gdTk $$Ifa$gdgr $$Ifa$gdgrkd$$Ifl0;#f ^ t0&644 lapytgrX Z f x xll` $$Ifa$gdTk $$Ifa$gdgrkd\$$Ifl0;#f ^ t0&644 lapytgr r xll`` $$Ifa$gdTk $$Ifa$gdgrkd$$Ifl0;#f ^ t0&644 lapytgr  ( , H L p t | ~    & ( 0 @ B L h p z ~u~u~u~hEQJaJo(hahEQJaJhTkQJaJo(hgrh RHZo(hgrh4z"o(hgrhaTVB*o(ph hgrh*& h<h  h<h< hgrhCihhgrhCiho( h<o(hgrh}o( h,h<h,h<o(hgrh o( hgrh .r t ~ xllllll $$Ifa$gdgrkd$$Ifl0;#f ^ t0&644 lapytgr  ( F:11 $Ifgd`uF $$Ifa$gdgrkdK$$Ifl\;}#f  /I t0&6 44 lap(ytgr 08>NRX\^hlnr|~ h9-&hEOJQJ^JaJh`uFOJQJ^JaJo(hEOJQJ^JaJo(h9-&hEOJQJ^JaJo(hEOJQJ^JaJhI;XQJaJo(h~thEQJaJo(h*QJaJo(hQJaJo(hahEQJaJhEQJaJo(0 &@B D\45RTfgx}ƿ~sjccccc h hEhEQJaJo(h+FhEQJaJ h+FhEh:mGhEo( hEo( h:mGhEhgrh RHZo(hgrh o(hgrhaTVB*o(ph hgrh  hEh`uFh OJQJ^JaJo(hyhEOJQJ^JaJhEOJQJ^JaJo(hyhEOJQJ^JaJo(&Bvj^U $Ifgd< $$Ifa$gdE $$Ifa$gdgrkd%$$Ifl0;#f ^ t0&644 lapytgr %()*036=WX|JLJL»hgrh o(hgrhtB*o(ph hgrhT hgrhT o( hgrh  hEh hEaJo( hr&RhE hShE h"IhE h9-&hE hB"hEhChEo( hChE hEo( h:mGhE4vm $IfgdCihkd$$Ifla0;#f ^ t0&644 lapytgrLxHxyjjjjjjjjjj$d $Ifa$gdo $$Ifa$gdgrykd$$Ifl-;#&  t 0&644 lap ytgr LXb$(6<DFJLNPxz|гЬгhoOJQJ^JaJo(hS06OJQJ^JaJ hdBhS06hS06OJQJ^JaJo(hdBhS06o(hS06hS06o( hS06o( hS06hS06 h18o( ho( hXl hXl hXl o( hOo(hdBh18o(:$*,.LNPRTVXnprF F"F$F&F(FþӤۘxvnini ho(hcsuho(U h/hXl hS06hS06hcsuhXl o(hXl B*o(ph hXl o( hXl hXl hXl h18B*phh ;kh18o( hB"h,7 h,7o(h18 h18o( h/h18hcsuh18o( hS06o( hXl hxhS06OJQJ^JaJo(hS06OJQJ^JaJ'PFy, 2007 HYPERLINK "javascript:;" Introduction to Protein. Beijing: science press, 2007. 0v] zSt 0 1u_g;N, yf[QHr>y, 2011Principles of enzyme engineering. 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